1
The current conventional view of intercostal muscle actions is based on the theory of Hamberger (1749) and maintains that as a result of the orientation of the muscle fibres, the external intercostals have an inspiratory action on the lung and the internal interosseous intercostals have an expiratory action. Recent studies in dogs, however, have shown that this notion is only approximate.
2
In the present studies, the respiratory actions of the human external and internal intercostal muscles were evaluated by applying the Maxwell reciprocity theorem. Thus the orientation of the muscle fibres relative to the ribs and the masses of the muscles were first assessed in cadavers. Five healthy individuals were then placed in a computed tomographic scanner to determine the geometry of the ribs and their precise transformation during passive inflation to total lung capacity. The fractional changes in length of lines with the orientation of the muscle fibres were then computed to obtain the mechanical advantages of the muscles. These values were finally multiplied by muscle mass and maximum active stress (3.0 kg cm⁻²) to evaluate the potential effects of the muscles on the lung.
3
The external intercostal in the dorsal half of the second interspace was found to have a large inspiratory effect. However, this effect decreases rapidly in the caudal direction, in particular in the ventral portion of the ribcage. As a result, it is reversed into an expiratory effect in the ventral half of the sixth and eighth interspaces.
4
The internal intercostals in the ventral half of the sixth and eighth interspaces have a large expiratory effect, but this effect decreases dorsally and cranially.
5
The total pressure generated by all the external intercostals during a maximum contraction would be -15 cmH₂O, and that generated by all the internal interosseous intercostals would be +40 cmH₂O. These pressure changes are substantially greater than those induced by the parasternal intercostal and triangularis sterni muscles, respectively.

References

Campbell, E. J. M. & Newsom Davis, J. (1970). The intercostal muscles and other muscles of the rib cage. In The Respiratory Muscles. Mechanics and Neural Control, 2nd edn, ed. E. J. M. Campbell, E. Agostoni & J. Newsom Davis, pp. 161–174. W. B. Saunders, Philadelphia.
Google Scholar
Close, R. I. (1972). Dynamic properties of mammalian skeletal muscles. Physiological Reviews 52, 129–197.
10.1152/physrev.1972.52.1.129
CASPubMedWeb of Science®Google Scholar
De Troyer, A. (1991). Inspiratory elevation of the ribs in the dog: primary role of the parasternals. Journal of Applied Physiology 70, 1447–1455.
PubMedWeb of Science®Google Scholar
De Troyer, A. & Kelly, S. (1982). Chest wall mechanics in dogs with acute diaphragm paralysis. Journal of Applied Physiology 53, 373–379.
10.1152/jappl.1982.53.2.373
PubMedWeb of Science®Google Scholar
De Troyer, A. & Legrand, A. (1995). Inhomogeneous activation of the parasternal intercostals during breathing. Journal of Applied Physiology 79, 55–62.
10.1152/jappl.1995.79.1.55
PubMedWeb of Science®Google Scholar
De Troyer, A. & Legrand, A. (1998). Mechanical advantage of the canine triangularis sterni. Journal of Applied Physiology 84, 562–568.
10.1152/jappl.1998.84.2.562
PubMedWeb of Science®Google Scholar
De Troyer, A., Legrand, A., Gevenois, P. A. & Wilson, T. A. (1998). Mechanical advantage of the human parasternal intercostal and triangularis sterni muscles. The Journal of Physiology 513, 915–925.
10.1111/j.1469-7793.1998.915ba.x
PubMedWeb of Science®Google Scholar
De Troyer, A., Legrand, A. & Wilson, T. A. (1996). Rostrocaudal gradient of mechanical advantage in the parasternal intercostal muscles of the dog. The Journal of Physiology 495, 239–246.
10.1113/jphysiol.1996.sp021588
PubMedWeb of Science®Google Scholar
De Troyer, A., Legrand, A. & Wilson, T. A. (1999). Respiratory mechanical advantage of the canine external and internal intercostal muscles. The Journal of Physiology 518, 283–289.
10.1111/j.1469-7793.1999.0283r.x
PubMedWeb of Science®Google Scholar
De Troyer, A. & Wilson, T. A. (2000). The canine parasternal and external intercostal muscles drive the ribs differently. The Journal of Physiology 523, 799–806.
10.1111/j.1469-7793.2000.00799.x
PubMedWeb of Science®Google Scholar
Farkas, G. A. (1991). Mechanical properties of respiratory muscles in primates. Respiration Physiology 86, 41–50.
10.1016/0034-5687(91)90038-K
CASPubMedWeb of Science®Google Scholar
Farkas, G. A., Decramer, M., Rochester, D. F. & De Troyer, A. (1985). Contractile properties of intercostal muscles and their functional significance. Journal of Applied Physiology 59, 528–535.
10.1152/jappl.1985.59.2.528
CASPubMedWeb of Science®Google Scholar
Gibson, G. J., Pride, N. B., O'Cain, C. & Quagliato, R. (1976). Sex and age differences in pulmonary mechanics in normal nonsmoking subjects. Journal of Applied Physiology 41, 20–25.
10.1152/jappl.1976.41.1.20
CASPubMedWeb of Science®Google Scholar
Hamberger, G. E. (1749). De Respirationis Mechanismo et usu Genuino. Iena.
Google Scholar
Legrand, A., Brancatisano, A., Decramer, M. & De Troyer, A. (1996). Rostrocaudal gradient of electrical activation in the parasternal intercostal muscles of the dog. The Journal of Physiology 495, 247–254.
10.1113/jphysiol.1996.sp021589
CASPubMedWeb of Science®Google Scholar
Legrand, A. & De Troyer, A. (1999). Spatial distribution of external and internal intercostal activity in dogs. The Journal of Physiology 518, 291–300.
10.1111/j.1469-7793.1999.0291r.x
CASPubMedWeb of Science®Google Scholar
Legrand, A., Ninane, V. & De Troyer, A. (1997). Mechanical advantage of sternomastoid and scalene muscles in dogs. Journal of Applied Physiology 82, 1517–1522.
10.1152/jappl.1997.82.5.1517
CASPubMedWeb of Science®Google Scholar
Legrand, A., Wilson, T. A. & De Troyer, A. (1996). Mediolateral gradient of mechanical advantage in the canine parasternal intercostals. Journal of Applied Physiology 80, 2097–2101.
CASPubMedWeb of Science®Google Scholar
Legrand, A., Wilson, T. A. & De Troyer, A. (1998). Rib cage muscle interaction in airway pressure generation. Journal of Applied Physiology 85, 198–203.
10.1152/jappl.1998.85.1.198
CASPubMedWeb of Science®Google Scholar
Margulies, S. S., Rodarte, J. R. & Hoffman, E. A. (1989). Geometry and kinematics of dog ribs. Journal of Applied Physiology 67, 707–712.
10.1152/jappl.1989.67.2.707
CASPubMedWeb of Science®Google Scholar
Saumarez, R. C. (1986). An analysis of possible movements of human upper rib cage. Journal of Applied Physiology 60, 678–689.
CASPubMedWeb of Science®Google Scholar
Sharp, J. T., Beard, G. A. T., Sunga, M., Kim, T. W., Modh, A., Lind, J. & Walsh, J. (1986). The rib cage in normal and emphysematous subjects: a roentgenographic approach. Journal of Applied Physiology 61, 2050–2059.
CASPubMedWeb of Science®Google Scholar
Taylor, A. (1960). The contribution of the intercostal muscles to the effort of respiration in man. The Journal of Physiology 151, 390–402.
10.1113/jphysiol.1960.sp006446
CASPubMedWeb of Science®Google Scholar
Turner, J. M., Mead, J. & Wohl, M. E. (1968). Elasticity of human lungs in relation to age. Journal of Applied Physiology 25, 664–671.
10.1152/jappl.1968.25.6.664
CASPubMedWeb of Science®Google Scholar
von Hayek, H. (1953). Die Menschliche Lunge. Springer-Verlag, Berlin , Germany .
10.1007/978-3-662-00649-8
Web of Science®Google Scholar
Wilson, T. A. & De Troyer, A. (1992). Effect of respiratory muscle tension on lung volume. Journal of Applied Physiology 73, 2283–2288.
10.1152/jappl.1992.73.6.2283
CASPubMedWeb of Science®Google Scholar
Wilson, T. A. & De Troyer, A. (1993). Respiratory effect of the intercostal muscles in the dog. Journal of Applied Physiology 75, 2636–2645.
10.1152/jappl.1993.75.6.2636
CASPubMedWeb of Science®Google Scholar
Wilson, T. A., Rehder, K., Krayer, S., Hoffman, E. A., Whitney, C. G. & Rodarte, J. R. (1987). Geometry and respiratory displacement of human ribs. Journal of Applied Physiology 62, 1872–1877.
CASPubMedWeb of Science®Google Scholar

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Volume530, Issue2

January 2001

Pages 319-330

Respiratory effects of the external and internal intercostal muscles in humans

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Respiratory effects of the external and internal intercostal muscles in humans

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