Early Investigator Prize 

The Journal of Physiology is pleased to offer an Early Investigator Prize. This initiative is designed to reward early career authors who publish outstanding research papers in The Journal. It is sponsored by both The Journal and our publishers Wiley-Blackwell.

The winning entries for this prize will be announced in The Journal of Physiology, on The Journal’s website and in Physiology News. The presentation of the 2016 winners will be made in 2017.

  • Applications are invited from scientists who are authors of a research article published in The Journal of Physiology during the prize year;
  • Entrants can be PhD students;
  • Entrants must have received their research degree (MD, PhD or equivalent) less than 6 years before submitting a paper;
  • Entrants who have had a career break should demonstrate that they have been in active research for fewer than six years in total since receiving their degree;
  • Where entrants have both an MD and PhD, the date of the most recently awarded degree will be applied;
  • Entries will be judged from the articles published during the year in The Journal of Physiology, by the Editorial Board;
  • The first prize will be $1000 and there are two runner’s up prizes of $500 each;
  • Where more than one Early Investigator has contributed to a winning paper, the prize will be split on the advice of the senior author;
  • Authors will be asked about their eligibility to enter this competition during submission.

If you meet the criteria of the above and wish to be considered for this Prize, at this stage please email jphysiol@physoc.org stating your name, qualifications and citing the volume and page numbers of The Journal in which your article is published. We will then log your interest and be in touch with you in due course.

2016 Results


Calum Wilson and Matthew Lee
Acetylcholine released by endothelial cells facilitates flow-mediated dilatation
Calum Wilson, Matthew D. Lee, John G. McCarron
J Physiol December 15, 2016 594 (24): 7267–7307. doi:10.1113/JP272927

Runners Up

Matthew S. Brook
Synchronous deficits in cumulative muscle protein synthesis and ribosomal biogenesis underlie age-related anabolic resistance to exercise in humans.
Matthew S. Brook, Daniel J. Wilkinson, William K. Mitchell, Jonathan N. Lund, Bethan E. Phillips, Nathaniel J. Szewczyk, Paul L. Greenhaff, Kenneth Smith, Philip J. Atherton
J Physiol, December 15, 2016 594 (24): 7399–7417. doi:10.1113/JP272857

David G.S. Farmer
Brainstem sources of cardiac vagal tone and respiratory sinus arrhythmia
David G.S. Farmer, Mathias Dutschmann, Julian F.R. Paton, Anthony E. Pickering, Robin M. McAllen
J Physiol, 594: 7249–7265. doi:10.1113/JP273164

Previous Winners



Calum Wilson - Pressure-dependent regulation of Ca2+ signalling in the vascular endothelium, by Calum Wilson, Christopher D. Saunter, John M. Girkin, John G. McCarron, J Physiol December 15, 2015 593 (24) 5231–5253

Runners Up

Esther Krook-Magnuson and Caren Armstrong - In vivo evaluation of the dentate gate theory in epilepsy, by Esther Krook-Magnuson, Caren Armstrong, Anh Bui, Sean Lew, Mikko Oijala, Ivan Soltesz, J Physiol May 15, 593 (10) 2379–2388

David Morales-Alamo - Limitations to oxygen transport and utilization during sprint exercise in humans: evidence for a functional reserve in muscle O2 diffusing capacity by José A. L. Calbet, José Losa-Reyna, Rafael Torres-Peralta, Peter Rasmussen, Jesús Gustavo Ponce-González, A. William Sheel, Jaime de la Calle-Herrero, Amelia Guadalupe-Grau, David Morales-Alamo, Teresa Fuentes, Lorena Rodríguez-García, Christoph Siebenmann, Robert Boushel, Carsten Lundby, J Physiol October 15, 593 (20) 4649–4664



Feng Yi - Direct excitation of parvalbumin-positive interneurons by M1 muscarinic acetylcholine receptors: roles in cellular excitability, inhibitory transmission and cognition, by  Feng Yi, Jackson Ball, Kurt E. Stoll, Vaishali C. Satpute, Samantha M. Mitchell, Jordan L. Pauli, Benjamin B. Holloway, April D. Johnston, Neil M. Nathanson, Karl Deisseroth, David J. Gerber, Susumu Tonegawa and J. Josh Lawrence, J Physiol August 15, 2014 592 (16) 3463-3494

Runners Up

Noah J. Marcus - Carotid body denervation improves autonomic and cardiac function and attenuates disordered breathing in congestive heart failure, by Noah J. Marcus, Rodrigo Del Rio, Evan P. Schultz, Xiao-Hong Xia and Harold D. Schultz, J Physiol January 14, 2014 592 (2) 391-408

Rodrigo Del Rio - Carotid body denervation improves autonomic and cardiac function and attenuates disordered breathing in congestive heart failure, by Noah J. Marcus, Rodrigo Del Rio, Evan P. Schultz, Xiao-Hong Xia and Harold D. Schultz, J Physiol January 14, 2014 592 (2) 391-408




Lasse Gliemann - Resveratrol blunts the positive effects of exercise training on cardiovascular health in aged men, by Lasse Gliemann, Jakob Friis Schmidt, Jesper Olesen, Rasmus Sjørup Biensø, Sebastian Louis Peronard, Simon Udsen Grandjean, Stefan Peter Mortensen, Michael Nyberg,  Jens Bangsbo, Henriette Pilegaard and Ylva Hellsten, J Physiol October 14, 2013 591 (20) 5047–5059

Runners Up

Aiste Adomaviciene - Putative pore-loops of TMEM16/anoctamin channels affect channel density in cell membranes, by Aiste Adomaviciene, Keith J. Smith, Hannah Garnett and Paolo Tammaro, J Physiol July 18, 2013 591 (14) 3487–3505

Daniel Wilkinson - Effects of leucine and its metabolite β-hydroxy-β-methylbutyrate on human skeletal muscle protein metabolism, by D. J. Wilkinson, T. Hossain, D. S. Hill, B. E. Phillips, H. Crossland, J. Williams, P. Loughna, T. A. Churchward-Venne, L. Breen, S. M. Phillips, T. Etheridge, J. A. Rathmacher, K. Smith, N. J. Szewczyk and P. J. Atherton, J Physiol May 31, 2013 591 (11) 2911–2923




Rahul Agrawal - Metabolic syndrome' in the brain: deficiency in omega-3 fatty acid exacerbates dysfunctions in insulin receptor signalling and cognition, by Rahul Agrawal and Fernando Gomez-Pinilla, J Physiol May 15, 2012 590 (10) 2485–2499

Runners Up 

Andrés Hernández - Dietary nitrate increases tetanic [Ca2+]i and contractile force in mouse fast-twitch muscle, by Andrés Hernández, Tomas A. Schiffer, Niklas Ivarsson, Arthur J. Cheng, Joseph D. Bruton, Jon O. Lundberg, Eddie Weitzberg andHåkan Westerblad, J Physiol July 27, 2012 590 (15) 3575–3583

Takashi Matsui - Brain glycogen supercompensation following exhaustive exercise, by Takashi Matsui, Taro Ishikawa, Hitoshi Ito, Masahiro Okamoto, Koshiro Inoue, Min-chul Lee, Takahiko Fujikawa, Yukio Ichitani, Kentaro Kawanaka and Hideaki Soya, J Physiol January 27, 2012 590 (3) 607–616

Funder Compliance

Editor's Choice

15 August - Volume 595 Issue 16

Paving the way for Bartter syndrome type 3 drug discovery: a hope from basic research
Paola Imbrici, Diana Conte, Antonella Liantonio

The eyes and vision of butterflies
Kentaro Arikawa

Endothelial mechanotransduction proteins and vascular function are altered by dietary sucrose supplementation in healthy young male subjects
Lasse Gliemann, Nicolai Rytter, Mads Lindskrog, Martina H. Lundberg Slingsby, Thorbjörn Åkerström, Lykke Sylow, Erik A. Richter, Ylva Hellsten

Functional severity of CLCNKB mutations correlates with phenotypes in patients with classic Bartter's syndrome
Chih‐Jen Cheng, Yi‐Fen Lo, Jen‐Chi Chen, Chou‐Long Huang, Shih‐Hua Lin

Sensory feedback from the urethra evokes state‐dependent lower urinary tract reflexes in rat
Zachary C. Danziger, Warren M. Grill