Symposium Issues

2016


EP November Issue

Immunity, atherogenesis and vascular function


Exp Physiol November 2016 Volume 101 Number 11

Syposium reports presented at the ISN Forefronts Symposium in Shenzhen, China, October 2016.
Overview by Jie Sun, Xiaolin Zhang and Xiong Z. Ruan

EP Sept cover

The brain in hypoxia; curiosity, cause and consequence

Exp Physiol September 2016 Volume 101 Number 9

Symposium reports presented at the Physiology 2015 meeting in Cardiff, July 2016.
Overview by Damian M. Bailey

Video slideshow introduction by Damian M. Bailey

EP Aug cover

Circadian regulation of cardiovascular and kidney function

Exp Physiol August 2016 Volume 101 Number 8

Symposium reports presented at the Physiology 2016 meeting in Dublin, July 2016.
Overview by David Pollock

Video slideshow introduction by David Pollock

EP

Gastro-Renal Communication

Exp Physiol April 2016 Volume 101 Number 4

Symposium reports presented at the Experimental Biology Meeting in April 2015.
Overview by Pedro Jose

Video slideshow introduction by Pedro Jose

EP

Sex hormone effects on autonomic and endothelial function

Exp Physiol March 2016 Volume 101 Number 3

Symposium reports presented at the Experimental Biology Meeting in April 2015.
Overview by Nina S. Stachenfeld

Video slideshow introduction by Nina S. Stachenfeld

EP

Sex differences in the physiology of exercise: an integrative perspective

Exp Physiol February 2016 Volume 101 Number 2

Symposium reports that were presented on 8 July 2015 at the Physiological Society meeting in Cardiff..
Overview by A. William Sheel

Video slideshow introduction by A. William Sheel

EP

Skeletal muscle adaptations to endurance training: is tissue hypoxia the main signal?

Exp Physiol January 2016 Volume 101 Number 1

From a symposium at the 2015 annual congress of the European College of Sport Sciences in Malmö, Sweden. organised by Carsten Lundby.
Overview by Carsten Lundby

Video slideshow introduction by Robert A Jacobs


2015


EP Oxygen transport issue cover

Oxygen transport adaptations to exercise in native highland populations
Exp Physiol November 2015 Volume 100 Number 11


From a symposium at organised by Peter Wagner and Tatum Simonson held at the Physiological Society Meeting in London, July 2014

Overview by Tatum Simonson 
Video slideshow introduction

EP

The Role of renal nerves in cardiovascular and renal function in normal and pathophysiological states
Exp Physiol 20th April 2015 - Volume 100 - Number 5

From a Symposium held on Renal Physiology

Overview by Ruy Campos and Cassia Bergamaschi
Video slide show introduction by by Clive May

EP

The heart is lost without the brain
Exp Physiol 1st April 2015 - Volume 100 - Number 4

From a Symposium held at the Physiological Society Meeting in London,
2nd July 2014

Overview by Susan Pyner
Video slide show introduction by Deputy Editor-in-chief Mark Chapleau

EP

The role of chemoreceptors during pathophysiology: from experimental
models to the clinical perspective

Exp Physiol 1st February 2015 - Volume 100 - Number 2

From a symposium held at The first Pan American congress of
Physiological Sciences
Physiology without Borders Iguassu Falls, Brazil in August 2014

Overview by Rodrigo del Rio
Video slide show

2014


EP

Novel regulatory mechanisms in muscle metabolism during exercise
Exp Physiol 1st December 2014 - Volume 99 - Number 12

From a symposium held at Physiology 2014,
Queen Elizabeth II Conference Centre, London, UK .

Overview by Erik Richter
Video slide show


EP

Physiological and pathophysiological signalling
between the gut and the kidney: role in diabetic kidney disease

Exp Physiol 10 September 2014 - Volume 99 - Number 9

From a symposium held at EB 2014
San Diego Convention Centre, San Diego, CA, USA on 30 April 2014.

Overview by Neil G. Docherty and Carel W. le Roux
Video slide show


EP

Contributions of skeletal muscle myopathy to heart failure:
Novel mechanisms and therapies   

Exp Physiol 1 April 2014 - Volume 99 - Number 4

Overview by Mark W. Chapleau
Slide show introduction

From a symposium held at IUPS 2013,
the XXXVII International Congress of Physiological Sciences,
Birmingham, UK on 22 July 2013.


EP

Myometrial physiology – time to translate?
Exp Physiol 1 March 2014 - Volume 99 - Number 3

Overview by Susan Wray and Jorge Carvajal
Slide show introduction

From a symposium held at IUPS 2013,
the XXXVII International Congress of Physiological Sciences,
Birmingham, UK on 25 July 2013.


EP

Brain–Heart Interactions in Health and Disease, a symposium
in honour of Professor John H. Coote

Exp Physiol 1 February 2014 - Volume 99 - Number 2

Overview by Thelma Lovick

From a symposium held at IUPS 2013,
the XXXVII International Congress of Physiological Sciences,
Birmingham, UK on 21 July 2013.


EP

The hypothalamic–neurohypophysial system: genomes, genes and genetics
January 2014 - Volume 99 - Number 1

Overview by Stephen Lolait
Slide show introduction

From a symposium held at the Tenth World Congress on Neurohypophysial Hormones, Bristol, UK, 19 July 2013.


2013


EP

The neuroendocrine regulation of the mammalian reproductive axis
November 2013 - Volume 98 - Number 11

Overview by W. H. Colledge
Slide show introduction

From a symposium held at Experimental Biology 2013, Boston, MA, USA.


EP

Hypoxic pulmonary hypertension: mechanisms of pulmonary vascular change and their effect on the right ventricle
August 2013 - Volume 98 - Number 8

Overview by P. McLoughlin and J. P. T. Ward
Slide show introduction

From a symposium held at IUPS 2013, the XXXVII International Congress of Physiological Sciences, Birmingham, UK
22 July 2013


EP

Advancing our understanding of the pathophysiology of cardiac disease using in vivo assessment of heart structure and function in rodent models
March 2013 - Volume 98 - Number 3

Overview by Christopher M. Loughrey and Gillian A. Gray
Slide show introduction

From a symposium held at Physiology 2012, the annual meeting of The Physiological Society on 5 July 2012, Edinburgh, UK


2012


EP

The neuroscience-systems biology disconnect: towards the NeuroPhysiome
April 2012 - Volume 97 - Number 4

Overview by Kendall F. Morris and James S. Schwaber

From the symposia Multi-scale modeling and systems biology of synapses and Multi-scale neuronal control of respiratory function: bridging gene networks to neural networks, held at Experimental Biology 2011
April 2011, Washington DC, USA


EP

The biomedical basis of elite performance
March 2012 - Volume 97 - Number 3

Overview by Mike White

From the symposia Cardiac, respiratory and vascular, Thermoregulation and Genomics and exercise held at the meeting The Biomedical Basis of Elite Performance
19-21 March 2011, London


EP

The anoctamin (TMEM16) gene family: calcium-activated chloride channels come of age  
February 2012 - Volume 97 - Number 2

Overview by John P. Winpenny and Michael A. Gray

From a symposium held at main meeting of The Physiological Society
13 July 2011, Oxford, UK


EP

Neural control of the circulation: Exercise
Janaury 2012 - Volume 97 - Number 1

Overview by Peter B. Raven

From a symposium to celebrate 40 years of the collaborative work of Goodwin, McCloskey and Mitchell, presented at a the annual meeting of The Physiological Society
July 2011, Oxford, UK


2011


EP

Emerging roles for gasotransmitters
September 2011- Volume 96 - Number 9

Overview by Chris Peers and David J. Lefer

From a symposium held at Experimental Biology 2011
April 2011, Washington, DC


EP

Glial–neuronal interactions in central nervous cardiovascular and respiratory control

Overview by Sergey Kasparov

April 2011 - Volume 96 - Number 4
From a symposium held at the main meeting of The Physiological Society
30 June 2010, Manchester, UK


2010


EP

Neurogenic hypertension
May 2010 - Volume 95 - Number 5

Overview by Julian F. R. Paton and Mohan K. Raizada

From the symposia Neurovascular inflammation and neurogenic hypertension, held at the main meeting of The Physiological Society, 7–10 July 2009, Dublin, Ireland; and Neurogenic hypertension, held at the XXXVI International Union of Physiological Sciences congress, 27 July–1 August 2009, Kyoto, Japan


EP

Adrenal corticosteroid effect in the central nervous system on the long-term control of blood pressure
January 2010- Volume 95 - Number 1

Overview by Deborah A. Scheuer

From a symposium held at Experimental Biology 2009
21 April 2009, New Orleans, LA, USA


EP

Direct assessment of organ specific sympathetic nervous system acivity in normal and cardiovascular disease states
January 2010- Volume 95 - Number 1

Overview by Mark M. Knuepfer and John W. Osborn

From a symposium held at Experimental Biology 2009
19 April 2009, New Orleans, LA, USA


2009


EP

Endothelial ageing: molecular mechanisms and functional significance
March 2009 - Volume 94 - Number 3

Overview by Margaret D. Brown

From a symposium held at the main meeting of The Physiological Society
16 July 2008, Cambridge, UK


EP

Mouse models for human epithelial disease: novel insights and new horizons
February 2009 - Volume 94 - Number 2

Overview by Peying Fong

From a symposium held at the main meeting of The Physiological Society
16 July 2008, Cambridge, UK


EP

Cotransmission in the autonomic nervous system
Janaury 2009 - Volume 94 - Number 1

Overview by Anja G. Teschemacher and Christopher D. Johnson

From a symposium held at the main meeting of The Physiological Society
16 July 2008, Cambridge, UK


2008


EP

Cerebrovascular function: changes in health and disease
Janaury 2008 - Volume 93 - Number 1

Overview by Douglas R. Corfield

From a symposium held at Life Sciences 2007, the combined annual meetings of The Physiological Society, the Biochemical Society and the British Pharmacological Society
10 July 2007, Glasgow, UK


2007


EP

Physiological genomics: from bench to bedside
November 2007 - Volume 92 - Number 6

Overview by Melinda R. Dwinell

From a symposium held at Experimental Biology 2007
29 April 2007, Washington, DC


EP

Neuroimmune interactions
September 2007 - Volume 92 - Number 5

Overview by Valeria Rettori

From a symposium held at Experimental Biology 2007
1 May 2007, Washington, DC


EP

Neural–glial–vascular communication in the brain
July 2007 - Volume 92 - Number 4

Overview by Jessica A. Filosa

From a symposium held at Experimental Biology 2007
29 April 2007, Washington, DC


EP

Hydromineral neuroendocrinology
May 2007 - Volume 92 - Number 3

Overview by Edward M. Stricker and Joseph G. Verbalis

From a symposium held at the International Congress of Neuroendocrinology
June 2006, Pittsburgh, PA, USA


EP

Muscle-energetic and cardio-pulmonary determinants of exercise tolerance in humans
March 2007 - Volume 92 - Number 2

Overview by Susan A. Ward

From a symposium held at the main meeting of The Physiological Society
July 2006, University College London, London, UK


2006


EP

Cover Image

Novel partners and mechanisms in oxygen sensing: Novel partners and mechanisms in oxygen sensing
September 2006 - Volume 91 - Number 5

Overview by Nanduri R. Prabhakar

From a symposium held at Experiemntal Biology 2006
3 April 2006, San Francisco, CA, USA


2005


EP

Neural mechanisms in obesity-related hypertension
September 2005 - Volume 90 - Number 5

Overview by R. A. L. Dampney

From a symposium on neural mechanisms in obesity-related hypertension, at the 25th Annual Meeting of the Australian Neuroscience Society in Perth in February, 2005


EP

New aspects of artery resistance and structure
July 2005 - Volume 90 - Number 4

Overview by Ian McGrath

From a Physiological Society sponsored symposium that took place during the meeting of the Spanish Physiological Society in Seville on 13 February 2005


EP

Cardiovascular–renal interactions: central and peripheral autonomic control
March 2005 - Volume 90 - Number 2

Overview

From a symposium a symposium held at the Physiological Society's meeting at University College Cork, Republic of Ireland, September 2004


EP

Viral gene transfer in neuroscience: new tricks of the trade
January 2005 - Volume 90 - Number 1

Overview by Sergey Kasparov and Julian F. R. Paton

From a symposium held at the University of Bristol, 4–5 September 2004


Funder Compliance


Monthly Editor’s pick

October - Volume 102 Issue 10

Circulating leucocytes perpetuate stroke-induced aortic dysfunction

Shinichi Asano, Grant C. O'Connell, Kent C. Lemaster, Evan R. DeVallance, Kayla W. Branyan, James W. Simpkins, Jefferson C. Frisbee,
Taura L. Barr, Paul D. Chantler

See all »

Experimental Biology joint virtual issue 2017

Joint Virtual Issue - Experimental Biology 2017

Reflecting the increasingly interdisciplinary nature of life science research, this collection brings together articles published in the journals of the Biochemical Society, the British Pharmacological Society, ASPET and The Physiological Society. Key topics highlighted include neurobiology, gastrointestinal biology, obesity, nutrition, and epigenetics.

All articles are free to read until 31 May. We hope you enjoy our collection!


Neurobiology

The repair Schwann cell and its function in regenerating nerves
The Journal of Physiology | K. R. Jessen & R. Mirsky | 10.1113/JP270874

What do we really know about newborn infant pain?
Experimental Physiology | Maria Fitzgerald | 10.1113/EP085134

Retrograde apoptotic signaling by the p75 neurotrophin receptor
Neuronal Signaling | Amrita Pathak & Bruce D. Carter  | 10.1042/NS20160007

Extracellular matrix inflammation in vascular cognitive impairment and dementia
Clinical Science | Gary A. Rosenberg | 10.1042/CS20160604

Ubiquitin C-terminal hydrolase L1 (UCH-L1): structure, distribution and roles in brain function and dysfunction
Biochemical Journal | Paul Bishop et al | 10.1042/BCJ20160082

Relaxin’ the brain: a case for targeting the nucleus incertus network and relaxin-3/RXFP3 system in neuropsychiatric disorders
British Journal of Clinical Pharmacology | Jigna Rajesh Kumar et al | 10.1111/bph.13564

Pharmacological comparison of a nonhuman primate and a rat model of oxaliplatin-induced neuropathic cold hypersensitivity
Pharmacology Research & Perspectives |Yuka Shidahara et al | 10.1002/prp2.216


Gastrointestinal biology

Endogenous and exogenous control of gastrointestinal epithelial function: building on the legacy of Bayliss and Starling
The Journal of Physiology | Kim E. Barrett | 10.1113/JP272227

Leptin modifies the prosecretory and prokinetic effects of the inflammatory cytokine interleukin-6 on colonic function in Sprague–Dawley rats
Experimental Physiology | Maria M. Buckleyet al | 10.1113/EP085917

Gastrointestinal transport of calcium and glucose in lactating ewes
Physiological Reports | Stefanie Klinger et al | 10.14814/phy2.12817

Foxa2 and Hif1ab regulate maturation of intestinal goblet cells by modulating agr2 expression in zebrafish embryos
Biochemical Journal | Yun-Ren Lai et al| 10.1042/BCJ20160392

Age-associated modifications of intestinal permeability and innate immunity in human small intestine
Clinical Science | Angela L. Mani et al|10.1042/CS20150046

Prescription behavior for gastroprotective drugs in new users as a result of communications regarding clopidogrel – proton pump inhibitor interaction
Pharmacology Research & Perspectives | Willemien J. Kruik-Kollöffel et al| 10.1002/prp2.242

Octreotide s.c. depot provides sustained octreotide bioavailability and similar IGF-1 suppression to octreotide LAR in healthy volunteers
British Journal of Clinical Pharmacology | F Tiberg et al| 10.1111/bcp.12698

Hydrogen sulphide protects against NSAID-enteropathy through modulation of bile and the microbiota
British Journal of Pharmocology |RW Blackler et al| 10.1111/bph.12961


Obesity

Resveratrol supplementation of high-fat diet-fed pregnant mice promotes brown and beige adipocyte development and prevents obesity in male offspring
The Journal of Physiology | Tiande Zou et al | 10.1113/JP273478

Oxidative stress and immunosenescence in spleen of obese mice can be reversed by 2-hydroxyoleic acid
Experimental Physiology | Alina Gheorghe et al | 10.1113/EP086157

Similar degrees of obesity induced by diet or aging cause strikingly different immunologic and metabolic outcomes
Physiological Reports | Kanthi B. Krishna at al | 0.14814/phy2.12708

Energy balalance, body composition, sedentariness and appetite regulation: pathways to obesity
Clinical Sciences | Mark Hopkins et al | 10.1042/CS20160006

New insight on obesity and adipose-derived stem cells using comprehensive metabolomics
Biochemical Journal |Annalaura Mastrangelo at al | 10.1042/BCJ20160241

A selective GPR40 (FFAR1) agonist LY2881835 provides immediate and durable glucose control in rodent models of type 2 diabetes
Pharmacology Research & Perspectives | Yanyun Chen et al | 10.1002/prp2.278

The effectiveness of pharmaceutical interventions for obesity: weight loss with orlistat and sibutramine in a United Kingdom population-based cohort
British Journal of Clinical Pharmocology | IJ Douglas et al | 10.1111/bcp.12578

Sodium butyrate epigenetically modulates high-fat diet-induced skeletal muscle mitochondrial adaptation, obesity and insulin resistance through nucleosome positioning
British Journal of Pharmocology | TM Henagan at al | 10.1111/bph.13058


Nutrition

Low carbohydrate, high fat diet impairs exercise economy and negates the performance benefit from intensified training in elite race walkers
The Journal of Physiology | Louise M. Burke et al | 10.1113/JP273230

Long term dietary quercetin enrichment as a cardioprotective countermeasure in mdx mice
Experimental Physiology | Christopher Ballmannl et al | 10.1113/EP086091

Undernutrition in pregnancy in mice leads to dysfunctional cardiac muscle respiration in adult offspring
Bioscience Reports |Brittany Beauchamp et al | 10.1042/BSR20150007

Blood triacylglycerols: a lipidomic window on diet and disease
Biochemical Society Transactions | Francis Saunders et al | 10.1042/BST20150235

The potential health effects of dietary phytoestrogens
British Journal of Pharmocology | Ivonne M C M Rietjens at al | 10.1111/bph.13622

Mediterranean diet, dietary polyphenols and low grade inflammation: results from the MOLI-SANI study
British Journal of Clinical Pharmocology |Marialaura Bonaccio at al | 10.1111/bcp.12924


Epigenetics

Late gestational intermittent hypoxia induces metabolic and epigenetic changes in male adult offspring mice
The Journal of Physiology |Abdelnaby Khalyfa et al | 10.1113/JP273570

Multigenerational effects of fetal-neonatal iron deficiency on hippocampal BDNF signaling
Physiological Reports | Mariah B. Blegen et al | 10.1002/phy2.96

Epigenetic inheritance of proteostasis and ageing
Essays in Biochemistry | Cheryl Li & Olivia Casanueva | 10.1042/EBC20160025

Epigenetic regulation of skeletal muscle metabolism
Clinical Science | Kirsten F Howlet &, Sean L McGee | 10.1042/CS20160115

A saga of cancer epigenetics: linking epigenetics to alternative splicing
Biochemical Journal| Sathiya Pandi Narayanan et al | 10.1042/BCJ20160147

Downregulation of the Ca2+-activated K+ channel KCa3.1 by histone deacetylase inhibition in human breast cancer cells
Pharmacology Research & Perspectivesl | Susumu Ohya et al | 10.1002/prp2.228

Therapeutic perspectives of epigenetically active nutrients
British Journal of Pharmocology | M Remely et al | 10.1111/bph.12854