Early Investigator Prize 

The Journal of Physiology is pleased to offer an Early Investigator Prize. This initiative is designed to reward early career authors who publish outstanding research papers in The Journal. It is sponsored by both The Journal and our publishers Wiley-Blackwell.

The winning entries for this prize will be announced in The Journal of Physiology, on The Journal’s website and in Physiology News. The presentation of the 2016 winners will be made in 2017.

  • Applications are invited from scientists who are authors of a research article published in The Journal of Physiology during the prize year;
  • Entrants can be PhD students;
  • Entrants must have received their research degree (MD, PhD or equivalent) less than 6 years before submitting a paper;
  • Entrants who have had a career break should demonstrate that they have been in active research for fewer than six years in total since receiving their degree;
  • Where entrants have both an MD and PhD, the date of the most recently awarded degree will be applied;
  • Entries will be judged from the articles published during the year in The Journal of Physiology, by the Editorial Board;
  • The first prize will be $1000 and there are two runner’s up prizes of $500 each;
  • Where more than one Early Investigator has contributed to a winning paper, the prize will be split on the advice of the senior author;
  • Authors will be asked about their eligibility to enter this competition during submission.

If you meet the criteria of the above and wish to be considered for this Prize, at this stage please email jphysiol@physoc.org stating your name, qualifications and citing the volume and page numbers of The Journal in which your article is published. We will then log your interest and be in touch with you in due course.

2016 Results


Calum Wilson and Matthew Lee
Acetylcholine released by endothelial cells facilitates flow-mediated dilatation
Calum Wilson, Matthew D. Lee, John G. McCarron
J Physiol December 15, 2016 594 (24): 7267–7307. doi:10.1113/JP272927

Runners Up

Matthew S. Brook
Synchronous deficits in cumulative muscle protein synthesis and ribosomal biogenesis underlie age-related anabolic resistance to exercise in humans.
Matthew S. Brook, Daniel J. Wilkinson, William K. Mitchell, Jonathan N. Lund, Bethan E. Phillips, Nathaniel J. Szewczyk, Paul L. Greenhaff, Kenneth Smith, Philip J. Atherton
J Physiol, December 15, 2016 594 (24): 7399–7417. doi:10.1113/JP272857

David G.S. Farmer
Brainstem sources of cardiac vagal tone and respiratory sinus arrhythmia
David G.S. Farmer, Mathias Dutschmann, Julian F.R. Paton, Anthony E. Pickering, Robin M. McAllen
J Physiol, 594: 7249–7265. doi:10.1113/JP273164

Previous Winners



Calum Wilson - Pressure-dependent regulation of Ca2+ signalling in the vascular endothelium, by Calum Wilson, Christopher D. Saunter, John M. Girkin, John G. McCarron, J Physiol December 15, 2015 593 (24) 5231–5253

Runners Up

Esther Krook-Magnuson and Caren Armstrong - In vivo evaluation of the dentate gate theory in epilepsy, by Esther Krook-Magnuson, Caren Armstrong, Anh Bui, Sean Lew, Mikko Oijala, Ivan Soltesz, J Physiol May 15, 593 (10) 2379–2388

David Morales-Alamo - Limitations to oxygen transport and utilization during sprint exercise in humans: evidence for a functional reserve in muscle O2 diffusing capacity by José A. L. Calbet, José Losa-Reyna, Rafael Torres-Peralta, Peter Rasmussen, Jesús Gustavo Ponce-González, A. William Sheel, Jaime de la Calle-Herrero, Amelia Guadalupe-Grau, David Morales-Alamo, Teresa Fuentes, Lorena Rodríguez-García, Christoph Siebenmann, Robert Boushel, Carsten Lundby, J Physiol October 15, 593 (20) 4649–4664



Feng Yi - Direct excitation of parvalbumin-positive interneurons by M1 muscarinic acetylcholine receptors: roles in cellular excitability, inhibitory transmission and cognition, by  Feng Yi, Jackson Ball, Kurt E. Stoll, Vaishali C. Satpute, Samantha M. Mitchell, Jordan L. Pauli, Benjamin B. Holloway, April D. Johnston, Neil M. Nathanson, Karl Deisseroth, David J. Gerber, Susumu Tonegawa and J. Josh Lawrence, J Physiol August 15, 2014 592 (16) 3463-3494

Runners Up

Noah J. Marcus - Carotid body denervation improves autonomic and cardiac function and attenuates disordered breathing in congestive heart failure, by Noah J. Marcus, Rodrigo Del Rio, Evan P. Schultz, Xiao-Hong Xia and Harold D. Schultz, J Physiol January 14, 2014 592 (2) 391-408

Rodrigo Del Rio - Carotid body denervation improves autonomic and cardiac function and attenuates disordered breathing in congestive heart failure, by Noah J. Marcus, Rodrigo Del Rio, Evan P. Schultz, Xiao-Hong Xia and Harold D. Schultz, J Physiol January 14, 2014 592 (2) 391-408




Lasse Gliemann - Resveratrol blunts the positive effects of exercise training on cardiovascular health in aged men, by Lasse Gliemann, Jakob Friis Schmidt, Jesper Olesen, Rasmus Sjørup Biensø, Sebastian Louis Peronard, Simon Udsen Grandjean, Stefan Peter Mortensen, Michael Nyberg,  Jens Bangsbo, Henriette Pilegaard and Ylva Hellsten, J Physiol October 14, 2013 591 (20) 5047–5059

Runners Up

Aiste Adomaviciene - Putative pore-loops of TMEM16/anoctamin channels affect channel density in cell membranes, by Aiste Adomaviciene, Keith J. Smith, Hannah Garnett and Paolo Tammaro, J Physiol July 18, 2013 591 (14) 3487–3505

Daniel Wilkinson - Effects of leucine and its metabolite β-hydroxy-β-methylbutyrate on human skeletal muscle protein metabolism, by D. J. Wilkinson, T. Hossain, D. S. Hill, B. E. Phillips, H. Crossland, J. Williams, P. Loughna, T. A. Churchward-Venne, L. Breen, S. M. Phillips, T. Etheridge, J. A. Rathmacher, K. Smith, N. J. Szewczyk and P. J. Atherton, J Physiol May 31, 2013 591 (11) 2911–2923




Rahul Agrawal - Metabolic syndrome' in the brain: deficiency in omega-3 fatty acid exacerbates dysfunctions in insulin receptor signalling and cognition, by Rahul Agrawal and Fernando Gomez-Pinilla, J Physiol May 15, 2012 590 (10) 2485–2499

Runners Up 

Andrés Hernández - Dietary nitrate increases tetanic [Ca2+]i and contractile force in mouse fast-twitch muscle, by Andrés Hernández, Tomas A. Schiffer, Niklas Ivarsson, Arthur J. Cheng, Joseph D. Bruton, Jon O. Lundberg, Eddie Weitzberg andHåkan Westerblad, J Physiol July 27, 2012 590 (15) 3575–3583

Takashi Matsui - Brain glycogen supercompensation following exhaustive exercise, by Takashi Matsui, Taro Ishikawa, Hitoshi Ito, Masahiro Okamoto, Koshiro Inoue, Min-chul Lee, Takahiko Fujikawa, Yukio Ichitani, Kentaro Kawanaka and Hideaki Soya, J Physiol January 27, 2012 590 (3) 607–616

Funder Compliance

Editor's Choice

15 October  - Volume 595 Issue 20

The kindlin-2 double act

Xi Ye, Kim A. Dora

Kindlin-2 interacts with endothelial adherens junctions to support vascular barrier integrity

Elzbieta Pluskota, Kamila M. Bledzka, Katarzyna Bialkowska, Dorota Szpak, Dmitry A. Soloviev, Sidney V. Jones, Dmitriy Verbovetskiy, Edward F. Plow

Chronic morphine reduces the readily releasable pool of GABA, a presynaptic mechanism of opioid tolerance

Adrianne R. Wilson‐Poe, Hyo‐Jin Jeong, Christopher W. Vaughan

Median preoptic glutamatergic neurons promote thermoregulatory heat loss and water consumption in mice

Stephen B. G. Abbott, Clifford B. Saper

See all »

Welcome to  The Journal of Physiology's first newsletter! 

Message from the Editor-in-Chief

In celebration of the one-year anniversary of the current editorial team taking the reins at The Journal of Physiology, we are pleased to send you the very first edition of our J Physiol newsletter. It does not seem possible that a year has already passed, but we also have got a lot done, and we're looking forward to being able to share J Physiol news with you on a regular basis - we will publish this newsletter quarterly. We hope that you find these items of interest, and we invite you to engage with us as you contemplate where to submit your research. Do not hesitate to contact me at any time if you have questions, comments or concerns about J Physiol ( kbarrett@ucsd.edu). I also hope to see many readers and authors at the 2017 Experimental Biology meeting in Chicago. And for real-time updates on the latest J Physiol content (and the Editor-in-Chief's musings on many other topics of the day), follow us on Twitter ( @JPhysiol and@jphysiol_eic) or sign up for email alerts of our Table of Contents. 
 Kim Barrett Editor-in-Chief
Going to Experimental Biology 2017? 
Meet Editor-in-Chief Kim Barrett at The Physiological Society's stand (#541) for beer and pizza!
Kim will be available to chat about your research interests and Sally Howells (Managing Editor) will be on hand for any questions you have about academic publishing. The session will be from 14:00 to 16:00 on Monday, 24 April.
Click here for more information.

Call for papers
We are seeking submissions for a special issue on Advances in cellular and integrative control of oxygen and carbon dioxide homeostasis. Email Sally Howells for more information.
Papers will relate to oxygen and carbon dioxide homeostasis from the cellular level to the whole organism. Examples may include but are not exclusive to the following topics:
  • Molecular responses to hypoxia and hypercapnia
  • O2/CO2 sensing in the carotid body
  • O2/CO2 sensing in the brain
  • Polymodal properties of arterial chemoreceptors
  • Adaptive and maladaptive responses to chronic or intermittent hypoxia
  • Role of chemoreception in disease
Special issue just published! 
K + channels and cardiac electrophysiology 
This issue contains two 'white papers that summarize consensus, controversies, and studies needed to fill gaps in our current knowledge. The first white paper ( Grandi et al., 2017) covers voltage gated K channel structural and function, K + channel expression, trafficking, localization, and regulation. The second white paper ( Chiamvimonvat et al., 2017) focuses on the functional roles of K + channels in health and disease, as well as K +channels as therapeutic targets. The issue endeavours to combine experimental and modelling studies, and to integrate knowledge at multiple scales from the single channels to cells to whole organ and animal levels. 

F1000Prime Recommendations
e have partnered with F1000Pr ime to offer readers free access to selected recommendations on J Physiolwork. The latest free recommendations can be accessed here.   
Online Collections
We are pleased to be able to assimilate some of our best content into online collections or 'virtual issues'. The content selected showcases the best research we have published on certain topics in the last 12 months.
Pre-submission enquiries
If you are unsure whether your research would fit within our scope, our Senior Editors will be pleased to offer advice prior to submission. Just email jphysiol@physoc.org with the title and abstract. 
Reasons to publish in J Physiol
What we offer authors
Not sure whether to submit your research to J Physiol? Check out some reasons below:
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  • Authors include 42 Nobel Prize winners
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